反应详情

A mixture of 5.0 g. of 6-(p-chlorophenyl)-3-chloropyridazine and 5.02 g. of 2-hydroxyethylhydrazine in 75 ml. of butanol is heated at reflux overnight and then cooled in an ice bath. The precipitate is collected by filtration, washed with butanol, water and then dried. Recrystallization from ethanol gives crystals, m.p. 172°-174° C.

1. additionA mixture of 5.0 g
2. temperatureat reflux overnight
3. temperaturecooled in an ice bath
4. filtrationThe precipitate is collected by filtration
5. washwashed with butanol, water
6. customdried
7. customRecrystallization from ethanol
8. customgives crystals, m.p. 172°-174° C.