2-Hydrazinoethanol → HCID 20326524, compound

HRID 372723Notes

Reaction equation

HRID 372723 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11](Cl)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[OH:15][CH2:16][CH2:17][NH:18][NH2:19]>C(O)CCC>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11]([N:18]([CH2:17][CH2:16][OH:15])[NH2:19])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 80172-HydrazinoethanolHCID 122575023-Chloro-6-(4-chlorophenyl)pyridazine

Product 1

HCID 20326524HCID 20326524, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A mixture of 5.0 g. of 6-(p-chlorophenyl)-3-chloropyridazine and 5.02 g. of 2-hydroxyethylhydrazine in 75 ml. of butanol is heated at reflux overnight and then cooled in an ice bath. The precipitate is collected by filtration, washed with butanol, water and then dried. Recrystallization from ethanol gives crystals, m.p. 172°-174° C.

Workup

  1. additionA mixture of 5.0 g
  2. temperatureat reflux overnight
  3. temperaturecooled in an ice bath
  4. filtrationThe precipitate is collected by filtration
  5. washwashed with butanol, water
  6. customdried
  7. customRecrystallization from ethanol
  8. customgives crystals, m.p. 172°-174° C.

Sources & evidence

ORD record
ord-6e692fb99758431eaf2478f41e5a82b0
Source dataset
uspto-grants-1978_05
Patent number
US04092311

Reaction notes

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