反应详情

Following the procedure of Example 5, a mixture of 5-(4-chlorobutyl)-3-phenyl-2-oxazolidinone (3.0 g, 0.01186 mol), 1-(2-pyridinyl)piperazine (1.94 g, 0.01186 mol), potassium carbonate (4.92 g, 0.0356 mol), and potassium iodide (1.0 g) in n-butanol (75 mL) gave an oil, which crystallized upon standing (3.9 g, 86% yield). The solid was recrystallized from isopropanol/isopropyl ether and dried under high vacuum to give 1.80 g, mp 78°-81° C.

1. customgave an oil, which
2. customcrystallized
3. customThe solid was recrystallized from isopropanol/isopropyl ether
4. customdried under high vacuum
5. customto give 1.80 g, mp 78°-81° C.