反应详情

To a solution of 2-bromonitrobenzene (10.23 g) in 1-propanol (100 ml) was added N,N-dimethylethylenediamine (13.41 g) and the mixture was refluxed for 3 days. The solvent was then distilled off under reduced pressure and the residue was purified by silica gel chromatography (eluent: chloroform:methanol=50:1) to give 9.72 g of N-(2-nitrophenyl)-N',N'-dimethylethylenediamine.

1. temperaturethe mixture was refluxed for 3 days
2. distillationThe solvent was then distilled off under reduced pressure
3. customthe residue was purified by silica gel chromatography (eluent: chloroform:methanol=50:1)