Triethylamine → HCID 131717619, compound

HRID 373107Notes

Reaction equation

HRID 373107 reaction equation
[CH3:1][N:2]1[C:9](=[O:10])[CH:8]([C:11](=[O:38])[NH:12][C:13]2[CH:18]=[C:17]([Cl:19])[C:16]([O:20][C:21]([F:36])([F:35])[CH:22]([O:24][C:25]([F:34])([F:33])[C:26]([F:32])([F:31])[C:27]([F:30])([F:29])[F:28])[F:23])=[C:15]([Cl:37])[CH:14]=2)[C:6](=[O:7])[N:5]([CH3:39])[C:3]1=[O:4].[CH2:40]([N:42]([CH2:45][CH3:46])[CH2:43][CH3:44])[CH3:41]>C(#N)C>[CH2:40]([NH+:42]([CH2:45][CH3:46])[CH2:43][CH3:44])[CH3:41].[CH3:39][N:5]1[C:6](=[O:7])[CH:8]([C:11](=[O:38])[NH:12][C:13]2[CH:14]=[C:15]([Cl:37])[C:16]([O:20][C:21]([F:36])([F:35])[CH:22]([O:24][C:25]([F:33])([F:34])[C:26]([F:31])([F:32])[C:27]([F:28])([F:29])[F:30])[F:23])=[C:17]([Cl:19])[CH:18]=2)[C:9](=[O:10])[N:2]([CH3:1])[C:3]1=[O:4]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 88506379HCID 88506379, compound

Product 1

HCID 131717619HCID 131717619, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

2.25 g (3.34 mmol) of 1,3-dimethyl-5-(3,5-dichloro-(4-(2-(1,1,2,2,3,3,3-heptafluoropropoxy)-1,1,2-trifluoroethoxy))-phenylcarbamoyl)-barbituric acid in 30 ml of acetonitrile were stirred with 0.38 g (3.7 mmol) of triethylamine at room temperature for 2 hours. The solution was concentrated and the residue was dried at 50° C. under an oil pump vacuum.

Workup

  1. concentrationThe solution was concentrated
  2. customthe residue was dried at 50° C. under an oil pump vacuum

Sources & evidence

ORD record
ord-9846186ce4e34853b50e85c3ecad3bfa
Source dataset
uspto-grants-1992_11
Patent number
US05162327

Reaction notes

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