Dimethyl Sulfate → HCID 19808761, compound

HRID 374026Notes

Reaction equation

[CH3:1][N:2]([CH3:24])[CH2:3][CH2:4][N:5]1[C:21](=[O:22])[C:20]2[C:19]3[C:18]4[C:13](=[CH:14][CH:15]=[C:16]([Cl:23])[CH:17]=4)[NH:12][C:11]=3[CH:10]=[CH:9][C:8]=2[C:6]1=[O:7].[H-].[Na+].S(OC)(O[CH3:31])(=O)=O>>[CH3:1][N:2]([CH3:24])[CH2:3][CH2:4][N:5]1[C:21](=[O:22])[C:20]2[C:19]3[C:18]4[C:13](=[CH:14][CH:15]=[C:16]([Cl:23])[CH:17]=4)[N:12]([CH3:31])[C:11]=3[CH:10]=[CH:9][C:8]=2[C:6]1=[O:7]

Participants

Reactant 3

HCID 6497Dimethyl Sulfate

HCID 24758Sodium hydride

HCID 6481892HCID 6481892, compound

Product 1

HCID 19808761HCID 19808761, compoundYield 60%

Procedure

400 mg of N-(2-dimethylaminoethyl)-6-chlorocarbazole-3,4-dicarboximide, 50 mg of 60% sodium hydride and 150 mg of dimethyl sulfate were subjected to the same reaction as in Example 3 (1) to obtain 250 mg (yield: 60%) of N-(2-dimethylaminoethyl)-6-chloro-9-methylcarbazole-3,4-dicarboximide as yellow crystals.

Sources & evidence

ORD record: ord-3e607f9a37ad491dbe9772722901f384
Source dataset: uspto-grants-1992_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05166204

Reaction notes

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