Methyl iodide → HCID 19808715, compound

HRID 374028Notes

Reaction equation

HRID 374028 reaction equation
[CH3:1][N:2]([CH3:24])[CH2:3][CH2:4][N:5]1[C:21](=[O:22])[C:20]2[C:19]3[C:18]4[C:13](=[CH:14][CH:15]=[C:16]([Cl:23])[CH:17]=4)[NH:12][C:11]=3[CH:10]=[CH:9][C:8]=2[C:6]1=[O:7].[CH3:25][I:26]>CN(C)C=O>[I-:26].[CH3:1][N+:2]([CH3:25])([CH3:24])[CH2:3][CH2:4][N:5]1[C:21](=[O:22])[C:20]2[C:19]3[C:18]4[C:13](=[CH:14][CH:15]=[C:16]([Cl:23])[CH:17]=4)[NH:12][C:11]=3[CH:10]=[CH:9][C:8]=2[C:6]1=[O:7]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 6481892HCID 6481892, compound

Product 1

HCID 19808715HCID 19808715, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In 10 ml of N,N-dimethylformamide was dissolved 200 mg of N-(2-dimethylaminoethyl)-6-chlorocarbazole-3,4-dicarboximide. Thereto was added 830 mg of methyl iodide. The mixture was stirred at room temperature for 2 hours. The resulting crystals were collected by filtration, washed with ethyl acetate, and dried to obtain 220 mg (yield: 78%) of N-(2-tri methylammonioethyl)-6-chlorocarbazole-3,4-dicarboximide iodide as yellow crystals.

Workup

  1. filtrationThe resulting crystals were collected by filtration
  2. washwashed with ethyl acetate
  3. customdried

Sources & evidence

ORD record
ord-7ecaf629985e4c709078a408f5ffc501
Source dataset
uspto-grants-1992_11
Patent number
US05166204

Reaction notes

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