Dimethylformamide → 6-Acetylbenzothiazolinone

HRID 374117Notes

Reaction equation

[Cl-].[Al+3].[Cl-].[Cl-].CN(C)C=O.[S:10]1(=[O:19])[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[CH:11]1.[C:20](Cl)(=[O:22])[CH3:21]>>[C:20]([C:16]1[CH:17]=[CH:18][C:13]2[N:12]=[CH:11][S:10](=[O:19])[C:14]=2[CH:15]=1)(=[O:22])[CH3:21]

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 6367Acetyl chloride

HCID 6451240Aluminum(III) Chloride

HCID 53400715Benzothiazolinone

Product 1

HCID 1317176216-Acetylbenzothiazolinone

Procedure

To a solution containing 0.5 mol of anhydrous aluminium chloride in 0.20 mol of dimethylformamide is added 0.05 mol of benzothiazolinone, then, slowly and with agitation, 0.06 mol of acetyl chloride.

Sources & evidence

ORD record: ord-1a451a7f8dbb4a2ba62b603aac1c8702
Source dataset: uspto-grants-1992_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05166353

Reaction notes

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