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HRID374403

反应详情

EQUATION

反应方程式

HRID 374403 的结构方程式

REACTANTS

反应物

4
结构：O=C([O-])[O-].[Na+].[Na+]
HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：C=C(C)C(=O)Cl
HCID13528

Methacryloyl chloride

C4H5ClO

结构：Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
HCID2723635

Glucosamine hydrochloride

C6H14ClNO5

结构：O=N[O-].[Na+]
HCID23668193

Sodium Nitrite

NNaO2

PRODUCTS

生成物

1
结构：C=C(C)C(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO
HCID22792501

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

Glucosamine hydrochloride ( 0.06 mol; 13.25 g), sodium carbonate (0.2 mol; 21.2 g) and sodium nitrite (0.2 g) were dissolved under nitrogen atmosphere at 0° C. in 100 ml of H2O. Methacryloyl chloride (0.12 mol; 13.0 g) was added under vigorous stirring. The reaction was carried out similar to the synthesis of 1 and gave the product as a white powder after two recrystallizations from water/ethanol/ether. Yield: 8.3-8.9 g (56-60%), p.m. (decomp.): 198°-199° C.

WORKUP

后处理

  1. customThe reaction was carried out similar to the synthesis of 1