Bromine → HCID 54395198, compound

HRID 374857Notes

Reaction equation

HRID 374857 reaction equation
[N+:1]([C:4]1[CH:10]=[C:9]([S:11][C:12]([F:15])([F:14])[F:13])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-:3])=[O:2].[Br:16]Br>FC(F)(F)C(O)=O.C(Cl)Cl>[Br:16][C:7]1[C:5]([NH2:6])=[C:4]([N+:1]([O-:3])=[O:2])[CH:10]=[C:9]([S:11][C:12]([F:15])([F:13])[F:14])[CH:8]=1

Participants

5

Reactant 2

HCID 24408BromineHCID 23279174HCID 23279174, compound

Product 1

HCID 54395198HCID 54395198, compound

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 6422Trifluoroacetic acidSolvent

Conditions

Temperature
40 °C

Procedure

24 g of finely powdered 2-nitro-4-trifluoromethylmercapto-aniline were dissolved in 50 ml of trifluoroacetic acid, and 18 g of bromine were metered in at 20° C. The mixture was then subsequently stirred at 20° C. for 3 hours and at 40° C. for a further 30 minutes and poured onto water, and the product was taken up in methylene chloride. After removal of the solvent, 31 g of 6-bromo-2-nitro-4-trifluoromethylmercapto-aniline were obtained.

Workup

  1. customwere metered in at 20° C
  2. additionpoured onto water
  3. customAfter removal of the solvent

Sources & evidence

ORD record
ord-628f28fbf4404b1599e9b77ed026fa42
Source dataset
uspto-grants-1996_01
Patent number
US05482956

Reaction notes

Loading…