Diethylamine → HCID 131719248, compound

HRID 375401Notes

Reaction equation

HRID 375401 reaction equation
N=[C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([C:13]([F:16])([F:15])[F:14])[CH:8]=2)[CH:5]=[C:4]([CH3:17])[S:3]1.C(NCC)C>CN(C)C=O>[F:16][C:13]([F:14])([F:15])[C:9]1[CH:8]=[C:7]([N:6]2[CH:5]=[C:4]([CH3:17])[S:3][CH2:2]2)[CH:12]=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 110215462(3H)-Thiazolimine, 5-methyl-3-[3-(trifluoromethyl)phenyl]-

Product 1

HCID 131719248HCID 131719248, compoundYield 68%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 2-imino-3-(3-trifluoromethylphenyl)-5-methylthiazoline (1.29 g, 5.0 mmol) and diethylamine (1.21 g, 16.5 mmol) in N,N-dimethylformamide (10 ml) charged in a reaction flask was reacted with the chlorotrifluoloethylene, which was made to flow into the flask (ca. 0.7 liter/hr), with vigorous stirring at room temperature for 6 hours. After completion of the reaction, the reaction mixture was subjected to a similar post-treatment as described above, which afforded 2-chlorofluoroacetylimino)-3-(3-trifluoromethylphenyl)-5-methylthiazoline (1.19 g, 3.4 mmol, yield 67% ).

Workup

  1. customwas reacted with the chlorotrifluoloethylene, which
  2. customAfter completion of the reaction

Sources & evidence

ORD record
ord-20e09b5edd9a465480eb247edd8e8b78
Source dataset
uspto-grants-1996_01
Patent number
US05484933

Reaction notes

Loading…