Oxalyl chloride → HCID 18993185, compound

HRID 375644Notes

Reaction equation

HRID 375644 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:16]=[C:15]3[C:11]([CH:12]=[CH:13][NH:14]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.C(Cl)(=O)[C:18](Cl)=[O:19]>CN(C=O)C>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:16]=[C:15]3[C:11]([CH:12]=[C:13]([CH:18]=[O:19])[NH:14]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 111066586-(4-FLUOROPHENYL)INDOLE

Product 1

HCID 18993185HCID 18993185, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The desired compound was prepared by Vilsmeier formylation of 6-(4-fluorophenyl)indole using DMF and oxalyl chloride.

Sources & evidence

ORD record
ord-6f09e4b377024cad8ee8740a01e5d5f2
Source dataset
uspto-grants-1996_01
Patent number
US05486525

Reaction notes

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