反应详情

A mixture of 5-acetamido-2-bromobenzoic acid (7 g, 27 mmol), DMF (25 ml), Cu(OAc)2 (0.2 g), 5-amino-1-ethyl-pyrazole (3 g, 27 mmol) and K2CO3 (3.7 g, 27 mmol) was refluxed for about 2 days. The reaction mixture was poured into water, acidified with acetic acid and cooled. A solid formed which was collected by filtration to afford 2 g of N-(1-ethylpyrazole-5-yl)-5-acetamidoanthranilic acid.

1. temperaturewas refluxed for about 2 days
2. temperaturecooled
3. customA solid formed which
4. filtrationwas collected by filtration