反应详情

5'-Fluoro-2'-formyl-4-methylthiobiphenyl (10 mmol) (Example 1E) in THF (20 ml) is charged dropwise with oxone® (6 mmol) and tetrabutylammonium hydrogensulfate (1 mmol) in water (15 ml). The mixture is stirred at room temperature for 1 hour. The suspension is poured into water (300 ml), the precipitate is filtered off, is washed with water and is dried in vacuo to give the title product.

1. filtrationthe precipitate is filtered off
2. washis washed with water
3. customis dried in vacuo