HRID37684

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID712

Formaldehyde

CH2O

HCID7005

1-Naphthol

C10H8O

HCID8082

Piperidine

C5H11N

HCID8083

Morpholine

C4H9NO

PRODUCTS

生成物

HCID241241

2-(Piperidinomethyl)-1-Naphthol

C16H19NO

HCID382950

1-Naphthalenol, 2-(4-morpholinylmethyl)-

C15H17NO2

PROCEDURE

实验过程

Anon. (USA) (Res. Discl., 236, 380 (Ger), 1983) discloses a Mannich reaction of 1-naphthol with formalin and piperidine or morpholine to yield 2-(piperidinomethyl)-1-naphthol or 2-(morpholinomethyl)-1-naphthol, respectively. These compounds were subjected to hydrogenolysis (Pd/C) whereby 2-methyl-1-naphthol was produced