反应详情

Phenyl N-(2-methoxyquinolin-3-yl)carbamate(148 mg, 0.5 mmol) and 1-(3,5-dimethoxyphenyl)piperazine(112 mg, 0.5 mmol) were dissolved in anhydrous tetrahydrofuran and DBU(117 mg, 0.75 mmol) was added. The solution was stirred at room temperature for 2 hours. The mixture was concentrated under the reduced pressure to remove tetrahydrofuran and purified by column chromatography(hexane:ether=5:1) to obtain the titled compound.

1. concentrationThe mixture was concentrated under the reduced pressure
2. customto remove tetrahydrofuran
3. custompurified by column chromatography(hexane:ether=5:1)