Bis(2-Methoxyethyl)amine → HCID 56622702, compound

HRID 378682Notes

Reaction equation

HRID 378682 reaction equation
[C:1]1([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:6]=[CH:5][C:4]([C:7]2[C:8](=[O:23])[N:9]3[C:14](=[C:15]([C:17]([OH:19])=O)[CH:16]=2)[C:13]2[S:20][CH:21]=[CH:22][C:12]=2[CH:11]=[CH:10]3)=[CH:3][CH:2]=1.O=S(Cl)Cl.C(N(CC)CC)C.[CH3:41][O:42][CH2:43][CH2:44][NH:45][CH2:46][CH2:47][O:48][CH3:49]>C1(C)C=CC=CC=1.ClCCl>[CH3:41][O:42][CH2:43][CH2:44][N:45]([CH2:46][CH2:47][O:48][CH3:49])[C:17]([C:15]1[CH:16]=[C:7]([C:4]2[CH:5]=[CH:6][C:1]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)=[CH:2][CH:3]=2)[C:8](=[O:23])[N:9]2[C:14]=1[C:13]1[S:20][CH:21]=[CH:22][C:12]=1[CH:11]=[CH:10]2)=[O:19]

Participants

7

Reactant 4

HCID 2383Bis(2-Methoxyethyl)amineHCID 8471TriethylamineHCID 24386Thionyl ChlorideHCID 19353607HCID 19353607, compound

Product 1

HCID 56622702HCID 56622702, compound

Reagents, catalysts & solvents 2

HCID 1140TolueneSolventHCID 6344DichloromethaneSolvent

Procedure

From 8-(biphenyl-4-yl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid with SOCl2 in toluene. Then treatment with triethylamine and bis(2-methoxyethyl)amine in dichloromethane.

Sources & evidence

ORD record
ord-d049098089b74033ad8fe3e366688cae
Source dataset
uspto-grants-2000_02
Patent number
US06030984

Reaction notes

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