Hydrogen Bromide → 4-Hydroxybenzylamine hydrobromide

HRID 378844Notes

Reaction equation

HRID 378844 reaction equation
C[O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][NH2:8])=[CH:5][CH:4]=1.[BrH:11]>>[BrH:11].[OH:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][NH2:8])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 754524-Methoxybenzylamine

Product 1

HCID 27592934-Hydroxybenzylamine hydrobromide

Procedure

4-Methoxybenzylamine (1.00 ml) in 48% HBr aq (10 ml) and heated at reflux for 10 hours. The cooled reaction mixture was filtered to give the sub-title compound (2.25 g).

Workup

  1. temperatureat reflux for 10 hours
  2. customThe cooled reaction mixture
  3. filtrationwas filtered

Sources & evidence

ORD record
ord-9e251b23b4d04659ab56c85ff3561791
Source dataset
uspto-grants-2001_10
Patent number
US06297232B1

Reaction notes

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