1-Indanone → HCID 378272, compound

HRID 378850Notes

Reaction equation

HRID 378850 reaction equation
[C:1]1(=[O:10])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[CH:11]([C:13]1[CH:22]=[CH:21][C:16]([C:17]([O:19][CH3:20])=[O:18])=[CH:15][CH:14]=1)=O.N1CCCCC1>C(O)(=O)C>[O:10]=[C:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[CH:11][C:13]1[CH:22]=[CH:21][C:16]([C:17]([O:19][CH3:20])=[O:18])=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 67351-IndanoneHCID 8082PiperidineHCID 15294Methyl 4-Formylbenzoate

Product 1

HCID 378272HCID 378272, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of indan-1-one (3.3 g), methyl 4-formylbenzoate (5.0 g), piperidine (0.6 ml) and glacial acetic acid (0.5 ml) was heated on a steam bath for 3 hours. The solid mass obtained was boiled up in industrial methylated spirits (200 ml) and then hot filtered. The solid residue obtained was washed with industrial methylated spirits and dried to give methyl 4-(1-oxoindan-2-ylidenemethyl)benzoate, m.p. 194-198° C.

Workup

  1. temperaturewas heated on a steam bath for 3 hours
  2. customThe solid mass obtained
  3. customThe solid residue obtained
  4. washwas washed with industrial methylated spirits
  5. customdried

Sources & evidence

ORD record
ord-484cea99540f449e8431864880a38c09
Source dataset
uspto-grants-2001_10
Patent number
US06297238B1

Reaction notes

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