HCID 21697270, compound → HCID 21697269, compound

HRID 378978Notes

Reaction equation

HRID 378978 reaction equation
[CH:1]1([O:6][C:7]2[CH:8]=[C:9]([C:18](=[O:29])[CH2:19][CH2:20][C:21]3[C:26]([Cl:27])=[CH:25][N:24]=[CH:23][C:22]=3[Cl:28])[C:10]([N+:15]([O-])=O)=[CH:11][C:12]=2[O:13][CH3:14])[CH2:5][CH2:4][CH2:3][CH2:2]1>C(O)(=O)C.[Fe]>[NH2:15][C:10]1[C:9]([C:18](=[O:29])[CH2:19][CH2:20][C:21]2[C:26]([Cl:27])=[CH:25][N:24]=[CH:23][C:22]=2[Cl:28])=[CH:8][C:7]([O:6][CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5]2)=[C:12]([O:13][CH3:14])[CH:11]=1

Participants

4

Reactant 1

HCID 21697270HCID 21697270, compound

Product 1

HCID 21697269HCID 21697269, compoundYield 75%

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 176Acetic AcidSolvent

Procedure

Operating analogously to example 31 using 1-(3-cyclopentyloxy-4-methoxy-6-nitro-phenyl)-2-(3,5-dichloro-pyridin-4-yl-methyl)-ethanone (26.75 g, 63 moles), obtained as described in example 38, and iron dust (21.1 g, 378 moles) in acetic acid (120 ml) 18.7 g of the title product were obtained (yield: 75%).

Workup

  1. customobtained

Sources & evidence

ORD record
ord-2dbcbb56a27648859a8a4e269a9150db
Source dataset
uspto-grants-2001_10
Patent number
US06297257B1

Reaction notes

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