Hydrogen Peroxide → HCID 178507375, compound

HRID 379528Notes

Reaction equation

HRID 379528 reaction equation
[NH2:1][C:2]1[C:10]2[N:9]=[N:8][NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[Br-:11].[K+].OO>C(O)(=O)C.[NH4+].[NH4+].[O-][Mo]([O-])(=O)=O>[NH2:1][C:2]1[C:10]2[N:9]=[N:8][NH:7][C:6]=2[C:5]([Br:11])=[CH:4][CH:3]=1

Participants

6

Reactant 3

HCID 784Hydrogen PeroxideHCID 253877Potassium BromideHCID 178507462HCID 178507462, compound

Product 1

HCID 178507375HCID 178507375, compoundYield 45.8%

Reagents, catalysts & solvents 2

HCID 61578Diammonium molybdateCatalystHCID 176Acetic AcidSolvent

Conditions

Temperature
25 °C

Procedure

To a solution of 4-aminobenzotriazole(550 milligram (hereinafter “mg”), 4.1 mmol) in acetic acid (10 ml) was added potassium bromide (520 mg, 4.4 mmol ), ammonium molybdate(67 mg, 0.55 mmol) and hydrogen peroxide (0.5 ml, 30%). The mixture was stirred at 25° C. for 3 hors. The solvent was evaporated and chromatography of the resulting solid on silica gel (EtOAc/Hexane(1equiv./1equiv.)) gave the desired product(400 mg, 45%). 1H NMR (CD3SO2CD3): δ7.29 (d, 1H), 6.49 (d, 1H), 6.05 (bs, 3H).

Workup

  1. customThe solvent was evaporated

Sources & evidence

ORD record
ord-1d8fb6779cd94ac0b03440c435c89267
Source dataset
uspto-grants-2001_10
Patent number
US06300325B1

Reaction notes

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