反应详情

温度

25 °C

To a solution of 4-aminobenzotriazole(550 milligram (hereinafter “mg”), 4.1 mmol) in acetic acid (10 ml) was added potassium bromide (520 mg, 4.4 mmol ), ammonium molybdate(67 mg, 0.55 mmol) and hydrogen peroxide (0.5 ml, 30%). The mixture was stirred at 25° C. for 3 hors. The solvent was evaporated and chromatography of the resulting solid on silica gel (EtOAc/Hexane(1equiv./1equiv.)) gave the desired product(400 mg, 45%). 1H NMR (CD3SO2CD3): δ7.29 (d, 1H), 6.49 (d, 1H), 6.05 (bs, 3H).

1. customThe solvent was evaporated