Potassium Bromide → HCID 18368119, compound

HRID 379802Notes

Reaction equation

HRID 379802 reaction equation
[C:1]([NH:4][C:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][C:12]=2[Cl:14])[N:7](C(OCC)=O)[C:6]=1[C:20](=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:3])[CH3:2].[K+].[Br-]>C(OCC)(=O)C.CCCCCC>[C:1]([NH:4][C:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][C:12]=2[Cl:14])[NH:7][C:6]=1[C:20](=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 253877Potassium BromideHCID 183678723-Acetylamino-2-benzoyl-4-chloro-1-(ethoxycarbonyl)indole

Product 1

HCID 18368119HCID 18368119, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 2 (Method A) from 3-acetylamino-2-benzoyl-4-chloro-1-(ethoxycarbonyl)indole (step 3). m.p.: 221-222° C. (ethyl acetate/hexane) 1H-NMR (CDCl3) δ: 9.12 (1H, br s), 7.82 (2H, d, J=7 Hz), 7.60-7.20 (6H, m), 7.12 (1H, d, J=7 Hz), 1.79 (3H, s) IR (KBr) ν: 3400, 3150, 1670, 1630, 1507, 1270, 780, 730 cm−1

Sources & evidence

ORD record
ord-daa6882c78df428cb44731809217ddaf
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

Loading…