m-Bromobenzenesulphonyl chloride → HCID 18367592, compound

HRID 379982Notes

Reaction equation

HRID 379982 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1.[Br:10][C:11]1[CH:12]=[C:13]([S:17]([Cl:20])(=[O:19])=[O:18])[CH:14]=[CH:15][CH:16]=1>CCOCC>[ClH:20].[Br:10][C:11]1[CH:12]=[C:13]([S:17]([NH:1][CH2:2][CH2:3][N:4]2[CH2:9][CH2:8][O:7][CH2:6][CH2:5]2)(=[O:19])=[O:18])[CH:14]=[CH:15][CH:16]=1

Participants

4

Reactant 2

HCID 17943m-Bromobenzenesulphonyl chlorideHCID 4082852-Morpholinoethylamine

Product 1

HCID 18367592HCID 18367592, compoundYield 59.1%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

4-(2-Aminoethyl)morpholine (2.54 g) was added, dropwise to a stirred solution of 3-bromobenzenesulphonyl chloride (5.0 g) in ether (50 ml) at 5° C. The resulting suspension was stirred for 30 minutes and filtered to afford the sub-titled compound as a solid (4.45 g)

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-c469a0099a874b08979df1542562e325
Source dataset
uspto-grants-2001_10
Patent number
US06300352B1

Reaction notes

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