4-Aminothiophenol → HCID 20693371, compound

HRID 380071Notes

Reaction equation

HRID 380071 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.[C:9]([O:13][C:14](=[O:17])[CH:15]=[CH2:16])([CH3:12])([CH3:11])[CH3:10]>O1CCCC1.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>[C:9]([O:13][C:14](=[O:17])[CH2:15][CH2:16][S:8][C:5]1[CH:6]=[CH:7][C:2]([NH2:1])=[CH:3][CH:4]=1)([CH3:12])([CH3:11])[CH3:10]

Participants

5

Reactant 2

HCID 145104-AminothiophenolHCID 15458tert-Butyl acrylate

Product 1

HCID 20693371HCID 20693371, compound

Reagents, catalysts & solvents 2

HCID 8028TetrahydrofuranSolvent2×HCID 2724141Tetrabutylammonium FluorideSolvent

Procedure

To a solution of 4-aminothiophenol (2.36 g) in tetrahydrofuran (THF; 20 ml), 2-propenoic acid t-butyl ester (3.51 ml) and 1.0M tetrabutylammonium fluoride in THF solution (340 μl) were added. The mixture solution was stirred for 30 minutes at room temperature to give the title compound. The compound was used for next reaction as such.

Sources & evidence

ORD record
ord-23f9daa70d264dc6b56fc72088adf0c6
Source dataset
uspto-grants-2001_10
Patent number
US06300514B1

Reaction notes

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