HCID 21779698, compound → HCID 18364729, compound

HRID 380514Notes

Reaction equation

HRID 380514 reaction equation
[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:5]=1[CH:11]=[CH2:12]>C(OCC)(=O)C.[Pd]>[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:5]=1[CH2:11][CH3:12]

Participants

4

Reactant 1

HCID 21779698HCID 21779698, compound

Product 1

HCID 18364729HCID 18364729, compoundYield 93.5%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A mixture of 0.105 g (0.6 mmol) of methyl-2-vinyl-3-methylbenzoate and 0.05 g of Pd/C 10% in 15 mL of ethyl acetate was hydrogenated at 50 psi for 2 h. The reaction mixture was filtered through a thin pad of celite and the filtrate was concentrated to give 0.1 g of the title compound.

Workup

  1. filtrationThe reaction mixture was filtered through a thin pad of celite
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-ddf0572280da4aa1a8f53d5f77874bcf
Source dataset
uspto-grants-2001_10
Patent number
US06303593B1

Reaction notes

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