Ethyl Acrylate → HCID 18365250, compound

HRID 380538Notes

Reaction equation

HRID 380538 reaction equation
[CH3:1][NH:2][CH:3]([CH3:10])[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6].[C:11]([O:15][CH2:16][CH3:17])(=[O:14])[CH:12]=[CH2:13]>>[CH3:1][N:2]([CH:3]([CH3:10])[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH2:13][CH2:12][C:11]([O:15][CH2:16][CH3:17])=[O:14]

Participants

3

Reactant 2

HCID 8821Ethyl AcrylateHCID 10396954HCID 10396954, compound

Product 1

HCID 18365250HCID 18365250, compoundYield 67.2%

Conditions

Temperature
110 °C

Procedure

A mixture of 54.4 gm (0.374 mole) ethyl 3-(N-methyl-amino)butanoate and 100 gm (0.999 mole) ethyl acrylate was heated at 110° C. with stirring for 18 hours. The reaction mixture was cooled to room temperature and then distilled under reduced pressure to provide 61.7 gm (67.1%) of the desired compound.

Workup

  1. temperatureThe reaction mixture was cooled to room temperature
  2. distillationdistilled under reduced pressure

Sources & evidence

ORD record
ord-2c904ad70673441f918ad7d0b557b80c
Source dataset
uspto-grants-2001_10
Patent number
US06303627B1

Reaction notes

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