Diethanolamine → HCID 12994567, compound

HRID 381679Notes

Reaction equation

HRID 381679 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8]Br)=[CH:4][C:3]=1[N:10]1[N:14]=[C:13]2[CH:15]=[CH:16][CH:17]=[CH:18][C:12]2=[N:11]1.[NH:19]([CH2:23][CH2:24][OH:25])[CH2:20][CH2:21][OH:22]>CC(C)=O>[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][N:19]([CH2:23][CH2:24][OH:25])[CH2:20][CH2:21][OH:22])=[CH:4][C:3]=1[N:10]1[N:14]=[C:13]2[CH:15]=[CH:16][CH:17]=[CH:18][C:12]2=[N:11]1

Participants

4

Reactant 2

HCID 8113DiethanolamineHCID 11162497HCID 11162497, compound

Product 1

HCID 12994567HCID 12994567, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Conditions

Temperature
75 °C

Procedure

2-(2′-Hydroxy-5′bromomethylphenyl)benzotriazole (3.03 g. 0.01 mole), diethanol amine (3.14 g. 0.03 mole) were dissolved in 100 ml. of acetone. The reaction mixture was refluxed with constant stirring at 75° C. for 6 h. The solvent was then removed by rotary evaporation. Crude product was purified using silica gel column chromatography Product was identified by 1H-NMR.

Workup

  1. temperatureThe reaction mixture was refluxed
  2. customThe solvent was then removed by rotary evaporation
  3. customCrude product was purified

Sources & evidence

ORD record
ord-52553da4d89a4553936a6f652a607a00
Source dataset
uspto-grants-2001_10
Patent number
US06307055B1

Reaction notes

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