反应详情

Methyl 3-t-butyl-4-hydroxy-5-methylsulfanylbenzoate (377 mg) was dissolved in N,N-dimethylformamide (7 mL), and potassium carbonate (818 mg) and dimethylsulfuric acid (0.32 mL) were added to the solution, and then the mixture was stirred at room temperature for 20 hours. Water was added to the reaction solution, and then the reaction mixture was extracted with ethyl acetate. The organic layer was washed with saturated brine, and then dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure to obtain the title compound (344 mg) as a pale yellow oily substance.

1. extractionthe reaction mixture was extracted with ethyl acetate
2. washThe organic layer was washed with saturated brine
3. dry with materialdried over anhydrous sodium sulfate
4. distillationThe solvent was distilled off under reduced pressure