Hydrochloric Acid → HCID 178465568, compound

HRID 386682Notes

Reaction equation

HRID 386682 reaction equation
C[O:2][C:3]1[N:8]=[CH:7][C:6]([C:9]2[O:10][C:11]3[CH:27]=[CH:26][C:25]([NH:28][C:29](=[NH:31])[CH3:30])=[CH:24][C:12]=3[C:13](=[O:23])[C:14]=2[O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:5][CH:4]=1.[ClH:32]>C(O)C>[ClH:32].[OH:2][C:3]1[N:8]=[CH:7][C:6]([C:9]2[O:10][C:11]3[CH:27]=[CH:26][C:25]([NH:28][C:29](=[NH:31])[CH3:30])=[CH:24][C:12]=3[C:13](=[O:23])[C:14]=2[O:15][CH2:16][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 178489182HCID 178489182, compound

Product 1

HCID 178465568HCID 178465568, compoundYield 40%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a suspension of 2-(6-methoxypyridin-3-yl)-3-benzyloxy-6-[(1-iminoethyl)amino]-4H-1-benzopyran-4-one (0.6 g) in ethanol (30 ml) was added HCl 6N (2 ml). The mixture was stirred under reflux for 30 hours, cooled and the hydrochloride was filtered off. Yield: 40%.

Workup

  1. temperatureunder reflux for 30 hours
  2. temperaturecooled
  3. filtrationthe hydrochloride was filtered off

Sources & evidence

ORD record
ord-bab89c2da4c048c181716edda633204d
Source dataset
uspto-grants-2013_02
Patent number
US08372866B2

Reaction notes

Loading…