HRID38688
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
CONDITIONS
反应条件
- 温度
- 65 °C
PROCEDURE
实验过程
To (6-methoxy-2′-phenylsulfanylmethyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester (0.24 mmol) in MeOH was added lithium hydroxide (a spatula tip), and the reaction was stirred at 65° C. overnight. After acidic work-up, the crude material was purified by preparative HPLC to give the title compound.
WORKUP
后处理
- customAfter acidic work-up, the crude material was purified by preparative HPLC