Diisopropylcarbodiimide → HCID 178503004, compound

HRID 386982Notes

Reaction equation

HRID 386982 reaction equation
[CH3:1][O:2][Si:3]([O:10][CH3:11])([O:8][CH3:9])[CH2:4][CH2:5][CH2:6][NH2:7].[CH:12]([N:15]=[C:16]=[N:17][CH:18]([CH3:20])[CH3:19])([CH3:14])[CH3:13]>>[CH:18]([NH:17][C:16]([NH:7][CH2:6][CH2:5][CH2:4][Si:3]([O:8][CH3:9])([O:10][CH3:11])[O:2][CH3:1])=[N:15][CH:12]([CH3:14])[CH3:13])([CH3:20])[CH3:19]

Participants

3

Reactant 2

HCID 12734DiisopropylcarbodiimideHCID 83756Aminopropyltrimethoxysilane

Product 1

HCID 178503004HCID 178503004, compound

Procedure

A mixture of 11.74 g of (3-(trimethoxysilyl)propyl)amine (0.0654 mol) and of 9.9 g of diisopropylcarbodiimide (0.0785 mol, 20% excess) was heated for 6 h 30 min at 80° C. Analysis by GC then showed an amine conversion of greater than 97%. The final colorless mixture was evaporated to dryness at 100° C. under 2 mbar for 2 h to give 22.5 g of a colorless, low-viscosity liquid corresponding to the expected guanidine.

Workup

  1. customThe final colorless mixture was evaporated to dryness at 100° C. under 2 mbar for 2 h

Sources & evidence

ORD record
ord-054b724107a040a58bde5d38a3801ed1
Source dataset
uspto-grants-2013_02
Patent number
US08372935B2

Reaction notes

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