huagongshe.com
HRID387005

反应详情

EQUATION

反应方程式

HRID 387005 的结构方程式

REACTANTS

反应物

4
结构：Cc1cccc(N2CCNCC2)c1C
HCID70541

1-(2,3-Xylyl)piperazine

C12H18N2

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+]
HCID5049666

Sodium triacetoxyborohydride

C6H10BNaO6

结构：O=CCCc1cc(-c2ccccc2)n(-c2ccccc2)n1
HCID42631135

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cccc(N2CCN(CCCc3cc(-c4ccccc4)n(-c4ccccc4)n3)CC2)c1C
HCID25065049

未命名化合物

PROCEDURE

实验过程

77 mg (81%) of target compound was obtained by using a method same as in Example 1 by using 3-(1,5-diphenyl-1H-pyrazol-3-yl)propanal (64 mg, 0.231 mmol), 1-(2,3-dimethylphenyl)piperazine (40 mg, 0.210 mmol), DIPEA (0.037 mL, 0.210 mmol) and NaBH(OAc)3 (156 mg, 0.735 mmol).

WORKUP

后处理

  1. custom77 mg (81%) of target compound was obtained