2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 59332625, compound

HRID 387315Notes

Reaction equation

HRID 387315 reaction equation
C(C1C(=O)C(Cl)=C(Cl)C(=O)C=1C#N)#N.[Br:15][C:16]1[C:17]([F:28])=[C:18]2[C:22](=[C:23]([C:25]([OH:27])=[O:26])[CH:24]=1)[NH:21][CH2:20][CH2:19]2>C(Cl)(Cl)Cl>[Br:15][C:16]1[C:17]([F:28])=[C:18]2[C:22](=[C:23]([C:25]([OH:27])=[O:26])[CH:24]=1)[NH:21][CH:20]=[CH:19]2

Participants

4

Reactant 2

HCID 67752,3-Dichloro-5,6-dicyano-1,4-benzoquinoneHCID 59332638HCID 59332638, compound

Product 1

HCID 59332625HCID 59332625, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

DDQ (17 mg, 0.075 mmol) was added to a solution of 5-bromo-4-fluoro-2,3-dihydro-1H-indole-7-carboxylic acid (17 mg, 0.066 mmol) in CHCl3 (2 mL) at room temperature. The reaction was stirred for 5 h and filtered. The precipitate was washed with CHCl3, and the filtrate was evaporated, giving the title compound.

Workup

  1. filtrationfiltered
  2. washThe precipitate was washed with CHCl3
  3. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-5f1d902aca3f4bf4a8ab86ae1bc60e8c
Source dataset
uspto-grants-2013_02
Patent number
US08372875B2

Reaction notes

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