反应详情

温度

60 °C

Trifluoroacetic acid anhydride (28.0 mL, 201 mmol) was added to a dichloroethane (300 mL) solution of the compound obtained in Example 20 (29.0 g, 89 mmol), and the mixture was stirred overnight at 60° C. The solvents were distilled off under a reduced pressure, and water was added to the residue. The precipitated crystals were separated by filtration and dried, to give 26.7 g (98%) of the captioned compound.

1. distillationThe solvents were distilled off under a reduced pressure, and water
2. additionwas added to the residue
3. customThe precipitated crystals were separated by filtration
4. customdried