Sodium Phosphate, Monobasic, Monohydrate → Pentasodium phosphate carbonate

HRID 389827Notes

Reaction equation

HRID 389827 reaction equation
O.[C:2](=[O:5])([O-:4])[O-:3].[Na+:6].[Na+].O.[OH:9][P:10]([O-:13])([OH:12])=[O:11].[Na+]>O>[C:2](=[O:3])([O-:5])[O-:4].[Na+:6].[Na+:6].[P:10]([O-:13])([O-:12])([O-:11])=[O:9].[Na+:6].[Na+:6].[Na+:6]

Participants

4

Reactant 2

HCID 516949Sodium Phosphate, Monobasic, MonohydrateHCID 2735133Sodium Carbonate Monohydrate

Product 1

HCID 22992644Pentasodium phosphate carbonate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Albumin (Human 25%, Plasbumin®-25 manufactured by Bayer Corporation) was buffered using differing amounts of Sodium Carbonate Monohydrate (Na2CO3H2O)(FW 124.00) (“Carbonate Buffer”) and Sodium Phosphate Monobasic Monohydrate (NaH2PO4H2O)(FW 137.99) (“Phosphate Buffer”). The buffered albumin formulations (2 cc) were mixed with 2 cc of the Shearwater PEG (0.45 g of PEG suspended in 2.2 cc of water), to provide 17% w/w PEG solids. The components were mixed by using the catheter device as generally shown in FIG. 2 (and as will be described in greater detail later). Upon mixing, the components were deposited in a test dish. The pH of the buffered albumin formulation (albumin plus buffer material) and the gelation time (as described above) and were recorded.

Workup

  1. customto provide 17% w/w PEG solids
  2. additionThe components were mixed
  3. additionUpon mixing

Sources & evidence

ORD record
ord-bcc0290cfb9146b4beb009e125561007
Source dataset
uspto-grants-2013_02
Patent number
US08383144B2

Reaction notes

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