反应详情

To a solution of 1-(3-methylphenyl)ethanone (2 g) in ethyl ether (20 mL) is added bromine (726 μL) at 0° C. The mixture is treated with an aqueous solution of sodium bicarbonate, extracted with ethyl ether, dried over magnesium sulfate, concentrated and purified on silica gel (ethyl acetate/cyclohexane 0/100) to give the desired compound.

1. extractionextracted with ethyl ether
2. dry with materialdried over magnesium sulfate
3. concentrationconcentrated
4. custompurified on silica gel (ethyl acetate/cyclohexane 0/100)