反应详情

A mixture of N-[3-(3-dimethoxymethyl-4-nitro-phenylsulfanyl)-phenyl]-benzenesulfonamide (0.027 mol) in 12N HCl (25 mL), THF (75 mL) and water (50 mL) was stirred overnight at room temperature, and then the mixture was extracted with ethyl acetate. The extract was washed with water and with a saturated aqueous Na2CO3 solution. The solvent was evaporated and the residue was purified by column chromatography over silica gel (eluent: CH2Cl2). The product fractions were collected and the solvent evaporated to yield the title compound as a residue.

1. extractionthe mixture was extracted with ethyl acetate
2. washThe extract was washed with water and with a saturated aqueous Na2CO3 solution
3. customThe solvent was evaporated
4. customthe residue was purified by column chromatography over silica gel (eluent: CH2Cl2)
5. customThe product fractions were collected
6. customthe solvent evaporated