反应详情

Preparation according to Preparation 22 using [7-(methylsulfonyl)-3,4-dihydro-2H-chromen-2-yl]methanol (0.4 g, 1.65 mmol), DCM (25 ml), p-toluenesulfonyl chloride (0.47 g, 2.5 mmol), TEA (0.28 ml, 2.0 mmol) and 4-DMAP (0.24 g, 2.0 mmol) stirred for overnight at room temperature. Yield: 0.59 g. MS m/z (rel. intensity, 70 eV) 419 (62), 416 (14), 415 (25), 414 (bp), 397 (M+1, 39).

1. customPreparation