Chloroacetamide → HCID 2858774, compound

HRID 393356Notes

Reaction equation

HRID 393356 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([S:10]([NH:13][CH2:14][C:15]([NH2:17])=[O:16])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].Cl[CH2:19][C:20]([NH2:22])=[O:21]>CN(C)C=O>[C:15]([CH2:14][N:13]([S:10]([C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)(=[O:12])=[O:11])[CH2:19][C:20]([NH2:22])=[O:21])(=[O:16])[NH2:17]

Participants

4

Procedure

reacting 2-(3-Nitro-benzenesulfonylamino)-acetamide with ClCH2CONH2 in the presence of N,N-Dimethylformamide and a base to provide 2-[Carbamoylmethyl-(3-nitro-benzenesulfonyl)-amino]acetamide;

Sources & evidence

ORD record
ord-8fb0669582cc479086e7373f91dfbe9f
Source dataset
uspto-grants-2004_10
Patent number
US06806366B2

Reaction notes

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