Triphenylphosphine → HCID 22648201, compound

HRID 394161Notes

Reaction equation

HRID 394161 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:17]=[C:16]([OH:18])[CH:15]=[C:14]2[C:9]=1[CH2:10][CH:11]([CH3:28])[C:12](=[O:27])[N:13]2[C:19]1[C:24]([Cl:25])=[CH:23][CH:22]=[CH:21][C:20]=1[Cl:26].C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.[N:48]1([CH2:54][CH2:55]O)[CH2:53][CH2:52][CH2:51][CH2:50][CH2:49]1>N(C(OCC)=O)=NC(OCC)=O>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:17]=[C:16]([O:18][CH2:55][CH2:54][N:48]2[CH2:53][CH2:52][CH2:51][CH2:50][CH2:49]2)[CH:15]=[C:14]2[C:9]=1[CH2:10][CH:11]([CH3:28])[C:12](=[O:27])[N:13]2[C:19]1[C:20]([Cl:26])=[CH:21][CH:22]=[CH:23][C:24]=1[Cl:25]

Participants

5

Reactant 3

HCID 11776TriphenylphosphineHCID 18232N-PiperidinoethanolHCID 22648136HCID 22648136, compound

Product 1

HCID 22648201HCID 22648201, compound

Reagents, catalysts & solvents 1

HCID 220568ethyl N-ethoxycarbonyliminocarbamateSolvent

Procedure

The title compound was prepared from 7 mg of 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydroxy-3-methyl-3,4-dihydroquinolin-2(1H)-one, 40 mg of Ph3P, 20 μL of 1-piperidine ethanol, and 20 μL of diethyl azodicarboxylate by a procedure analogous to that described in EXAMPLE 2. Mass spectrum (ESI) 545 (M+1).

Sources & evidence

ORD record
ord-b7cea77af76b4ca9a84e58332ea799c1
Source dataset
uspto-grants-2004_10
Patent number
US06809199B2

Reaction notes

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