Hydrochloric Acid → 1-(4-Chlorophenyl)-3-methyl-1H-pyrazole

HRID 394776Notes

Reaction equation

HRID 394776 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.Cl.[C:11]1(NN)[CH:16]=CC=[CH:13][CH:12]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:16]=[CH:11][C:12]([CH3:13])=[N:9]2)=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 7516PhenylhydrazineHCID 70624(4-Chlorophenyl)hydrazine

Product 1

HCID 179399681-(4-Chlorophenyl)-3-methyl-1H-pyrazole

Procedure

This compound was prepared by the same methodology described for EXAMPLE 1 with 4-chlorophenyl hydrazine.HCl substituted for phenyl hydrazine. There was obtained 1-(4′-chlorophenyl)-3-methyl-1H-pyrazole-5-[(2′-aminosulfonyl-[1,1′]-biphen-4-yl)carboxyamide; HRMS (M+H)+: calc. 467.094465; found 467.093532.

Workup

  1. customThis compound was prepared by the same methodology

Sources & evidence

ORD record
ord-c5431b08d2b94feba2fa592a2797ec16
Source dataset
uspto-grants-2003_08
Patent number
US06602895B2

Reaction notes

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