反应详情

1.76 g (10 mmol) of 4-allyloxyacetophenone and 1.66 g (10 mmol) of 2,3-dimethoxy-benzaldehyde were under an inert atmosphere (argon) dissolved in 10 ml of dry freshly distilled ethanol, and 100 mg of sodium hydroxide was added to the solution. The mixture was left under stirring for 23 h and concentrated in vacuo. The crystalline residue was recrystallized from methanol-water to give 2.92 g (90%) of 2,3-dimethoxy-4′-prop-2-enyloxychalcone, m.p. 98-99° C.

1. dissolutiondissolved in 10 ml
2. dry with materialof dry freshly distilled ethanol, and 100 mg of sodium hydroxide
3. additionwas added to the solution
4. waitThe mixture was left
5. concentrationconcentrated in vacuo
6. customThe crystalline residue was recrystallized from methanol-water