Hydrochloric Acid → Ethyl cyclopropanecarboximidate hydrochloride

HRID 397948Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 397948
[ClH:1].[CH:2]1([C:5]#[N:6])[CH2:4][CH2:3]1.[CH2:7]([O:9]CC)[CH3:8]>CCO>[ClH:1].[CH2:7]([O:9][C:5]([CH:2]1[CH2:4][CH2:3]1)=[NH:6])[CH3:8]

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 79637Cyclopropanecarbonitrile

Produkt 1

HCID 20026660Ethyl cyclopropanecarboximidate hydrochlorideAusbeute 59 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

A steady stream of HCl gas was slowly passed through a solution of cyclopropancarbonitril (25 g, 373 mmol) in EtOH (17.2 ml). After 15 h the reaction mixture was cooled to 0° C. and diethylether was added dropwise. The precipitated title compound was filtered and obtained as a colourless crystalline material (32.9 g, 220 mmol, 59%). MS: m/e=112.2 (M−H).

Aufarbeitung

  1. customThe precipitated title compound
  2. filtrationwas filtered

Quellen und Nachweise

ORD-Eintrag
ord-82b83684b24e4704b279c0b7d2caca4b
Quelldatensatz
uspto-grants-2003_08
Patentnummer
US06610723B2

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