Chloride → HCID 23002571, compound

HRID 398260Notes

Reaction equation

HRID 398260 reaction equation
[OH-].[Na+].[CH2:3]([CH:5]([CH2:9][CH2:10][CH2:11][CH3:12])[C:6]([OH:8])=[O:7])[CH3:4].[Cl-].Cl[C:15]([O:17][CH3:18])=[O:16]>O>[C:15](=[O:16])([O:17][CH3:18])[O:7][C:6](=[O:8])[CH:5]([CH2:3][CH3:4])[CH2:9][CH2:10][CH2:11][CH3:12]

Participants

6

Reactant 4

HCID 312ChlorideHCID 6586Methyl chloroformateHCID 86972-Ethylhexanoic AcidHCID 14798Sodium Hydroxide

Product 1

HCID 23002571HCID 23002571, compoundYield 100.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a well-stirred reaction vessel equipped with a thermometer and a pH electrode were added 45 g of water, 0.075 mole of a 33 wt % aqueous NaOH solution, 0.075 mole of 2-ethylhexanoic acid, and 0.23 g of Arquad CB50 (i.e. cocobenzyldimethylammonium chloride, ex Akzo Nobel) at 5° C. 0.075 mole of methyl chloroformate was dosed in 5 min at 5° C. The mixture was post-reacted for 30 min at 5° C. and a pH of 8. Then, the water layer was separated, giving 15.2 g of 2-ethylhexanoyl methyl carbonate having a content of 99.5% (determined by NMR) in a yield of 99.6%.

Workup

  1. customTo a well-stirred reaction vessel
  2. customequipped with a thermometer
  3. customThe mixture was post-reacted for 30 min at 5° C.
  4. customThen, the water layer was separated

Sources & evidence

ORD record
ord-c3d3daf8dfb145b08c999259e4e8755f
Source dataset
uspto-grants-2003_08
Patent number
US06610880B1

Reaction notes

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