Dimethylformamide → HCID 54259741, compound

HRID 398336Notes

Reaction equation

HRID 398336 reaction equation
[C:1]([C:3]1[CH:8]=[C:7]([CH3:9])[C:6]([N+:10]([O-:12])=[O:11])=[CH:5][N:4]=1)#[N:2].[CH3:13][N:14]([CH:16]=O)[CH3:15]>>[C:1]([C:3]1[CH:8]=[C:7]([CH:9]=[CH:13][N:14]([CH3:16])[CH3:15])[C:6]([N+:10]([O-:12])=[O:11])=[CH:5][N:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 6228DimethylformamideHCID 230001714-Methyl-5-nitropyridine-2-carbonitrile

Product 1

HCID 54259741HCID 54259741, compound

Procedure

A stirred solution of 2-cyano-4-methyl-5-nitropyridine (2.48 g, 15.2 mmol) in DMF (10 mL) and DMF-dimethylacetal (2.7 mL, 20 mmol) was heated to 90° C. for two h. The solution was cooled and evaporated in vacuo to give the title compound as a deep red solid:

Workup

  1. temperatureThe solution was cooled
  2. customevaporated in vacuo

Sources & evidence

ORD record
ord-29dd05ebc4b9480cae3bc0def21340b0
Source dataset
uspto-grants-2003_08
Patent number
US06610692B1

Reaction notes

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