反应详情

温度

100 °C

13.2 Grams of octadecanethiol, 14.3 g of 11-bromoundecanamide, 1.7 g of potassium iodide, 20.7 g of potassium carbonate and 100 ml of N,N-dimethylacetamide were charged in a flask equipped with a stirrer, a condenser and a calcium chloride drying tube and stirred with heating at 100° C. for 5 hours. The reaction mixture was cooled to room temperature and, then, introduced into ice water, and the precipitated crystal was filtered off under reduced pressure and washed with distilled water. The crystal was recrystallized from 2-propanol to obtain 16.4 g of the desired product. m.p. 108° C.

1. customequipped with a stirrer, a condenser and a calcium chloride drying tube
2. temperatureThe reaction mixture was cooled to room temperature
3. filtrationthe precipitated crystal was filtered off under reduced pressure
4. washwashed with distilled water
5. customThe crystal was recrystallized from 2-propanol