1-Pentyne → HCID 11137342, compound

HRID 399358Notes

Reaction equation

HRID 399358 reaction equation
[CH:1]#[C:2][CH2:3][CH2:4][CH3:5].C([Li])CCC.Br[C:12]1[S:13][CH:14]=[CH:15][CH:16]=1>[Cl-].[Zn+2].[Cl-]>[C:1]([C:12]1[S:13][CH:14]=[CH:15][CH:16]=1)#[C:2][CH2:3][CH2:4][CH3:5]

Participants

5

Reactant 3

HCID 123091-PentyneHCID 138512-BromothiopheneHCID 178418339Butyllithium

Product 1

HCID 11137342HCID 11137342, compound

Reagents, catalysts & solvents 1

HCID 3007855ZincchlorideCatalyst

Procedure

Quantities: pent-1-yne (6.80 g, 0.10 mol), n-butyllithium (10.0 ml, 10.0M in hexane, 0.044 mol), zinc chloride (13.60 g, 0.10 mol), 2-bromothiophene (16.00 g, 0.098 mol), tetrakis (triphenylphosphine)palladium(O) (3.40 g 2.94 mol).

Sources & evidence

ORD record
ord-62deb6676c1f4f969ce22e4eaded88e9
Source dataset
uspto-grants-1998_10
Patent number
US05820781

Reaction notes

Loading…