反应详情

This experimental procedure is an O-alkylation. A solution of bromomethane (48.90 g, 0.45 mol) is added dropwise to a stirred refluxing mixture of 6-Bromo-2-naphthol (40.00 g, 0.18 mol) and potassium carbonate (63.00 g, 0.46 mol) in acetone. The stirred mixture is heated under reflux for 24 hours (ie until glc analysis reveals a complete reaction). The potassium carbonate is filtered off, water is added to filtrate and the product is recrystallised from ethanol to give a yield of 43.92 g (97%).

1. temperaturerefluxing
2. temperatureThe stirred mixture is heated
3. temperatureunder reflux for 24 hours (ie until glc analysis
4. customa complete reaction)
5. filtrationThe potassium carbonate is filtered off
6. additionwater is added to filtrate
7. customthe product is recrystallised from ethanol
8. customto give a yield of 43.92 g (97%)