HCID 86753214, compound → HCID 18665857, compound

HRID 399437Notes

Reaction equation

HRID 399437 reaction equation
[CH2:1]([NH:5][S:6]([NH:9][C@@H:10]([CH2:16][NH:17]C(OC(C)(C)C)=O)[C:11]([O:13][CH2:14][CH3:15])=[O:12])(=[O:8])=[O:7])[CH2:2][CH2:3][CH3:4]>C(OCC)(=O)C>[CH2:1]([NH:5][S:6]([NH:9][C@@H:10]([CH2:16][NH2:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12])(=[O:7])=[O:8])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 86753214HCID 86753214, compound

Product 1

HCID 18665857HCID 18665857, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 9-2 (612 mg, 1.65 mmol) in ethyl acetate (50 ml) was cooled to -5° and anhydrous HCl was bubbled in for 30 min. The reaction was concentrated and the product isolated by filtration to give 9-3 as a white solid.

Workup

  1. customanhydrous HCl was bubbled in for 30 min
  2. concentrationThe reaction was concentrated
  3. customthe product isolated by filtration

Sources & evidence

ORD record
ord-ee56789f8e164366bf553197365c0992
Source dataset
uspto-grants-1998_10
Patent number
US05821241

Reaction notes

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