Ethyl Bromide → HCID 18944861, compound

HRID 399716Notes

Reaction equation

HRID 399716 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([CH3:17])[C:11](=[O:12])[NH:10][C:9]2[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=2[O:7]1)=[O:5])[CH3:2].[CH2:18](Br)[CH3:19]>>[CH2:1]([O:3][C:4]([C:6]1([CH3:17])[C:11](=[O:12])[N:10]([CH2:18][CH3:19])[C:9]2[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=2[O:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 6332Ethyl BromideHCID 3378326Ethyl 2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate

Product 1

HCID 18944861HCID 18944861, compound

Procedure

The title compound was prepared from ethyl-3,4-dihydro-2-methyl-3-oxo-2H-1,4-benzoxazine-2-carboxylate and ethyl bromide according to the procedure described in Example 16. The title product was a viscous oil, which was purified by column chromatography (silica gel; dichloromethane/methanol 100:1).

Workup

  1. customwas purified by column chromatography (silica gel; dichloromethane/methanol 100:1)

Sources & evidence

ORD record
ord-76ab090f3d874a6bab89c6a355165081
Source dataset
uspto-grants-1998_10
Patent number
US05824652

Reaction notes

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