反应详情

Methanesulfonic acid (0.8 ml) was added to a mixture of 2-[3-(2-cyanopyrrol-1-yl)benzoyl]guanidine (2.0 g) in methanol (20 ml) and the mixture was stirred for 30 minutes at ambient temperature. To the mixture was added ethyl acetate (20 ml) and isolated precipitate was collected by filtration. The precipitate was recrystallized from water to give 2-[3-(2-cyanopyrrol-1-yl)benzoyl]guanidine methanesulfonate (1.48 g).

1. customisolated precipitate
2. filtrationwas collected by filtration
3. customThe precipitate was recrystallized from water